When I was a kid, my Dad volunteered to try to see if orphaned coyote pups could be tamed. Someone had shot the pups mother and the Utah Fish & Game tried to find a way to keep the pups alive. They were down in our basement. My Dad would handle them everyday. After a short time, the only one he could pick up was a sickly one. The healthy ones were to aggressive. Eventually, the sick one bit his thumb through thick leather gloves. He finally decided that it just wouldn't work and had to turn them back to the Fish & Game. Boy, did our basement smell gamey; the wildest odor you could imagine.
This is a photo of the pups by their den before they were taken.